The utility mode relates to an anti-leakage device of a hygienic product. The anti-leakage device comprises that an outer layer is a protection layer and a decoration layer, a middle layer of water absorbent materials is arranged on the protection layer, a third layer of a ventilation anti-leakage structure is arranged on the middle layer, and a forth layer of a skin contact layer is arranged on the third layer. A plurality of ventilation guide pipes with lengths determined according to sizes of products are staggered on a ventilation anti-leakage portion of the third layer, air holes at top ends of the ventilation guide pipes penetrate through the outer layer and the middle layer and are exposed outside. Anti-leakage valves and leakage holes are arranged on the ventilation guide pipes, inside and outside air enters the anti-leakage valves and the leakage holes penetrating through the ventilation guide pipes, and a blast chamber is arranged outside the anti-leakage valves. The anti-leakage device is applicable to baby diapers and protection pads and hygienic products used through special structures in pollution factories, projects or work places.